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APG101 efficiently rescues erythropoiesis in lower risk myelodysplastic syndromes with severe impairment of hematopoiesis
CD95, a member of the death receptor family initiates a caspase-dependent apoptosis, when activated by its ligand CD95L, thought to negatively regulate erythrocyte production in the bone marrow. We have previously shown that CD95 is overexpressed in two thirds of patients with a lower risk myelodysp...
Autores principales: | Raimbault, Anna, Pierre-Eugene, Cecile, Rouquette, Alexandra, Deudon, Celine, Willems, Lise, Chapuis, Nicolas, Mathis, Stephanie, Kunz, Claudia, Fricke, Harald, Kosmider, Olivier, Bardet, Valerie, Fontenay, Michaela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924760/ https://www.ncbi.nlm.nih.gov/pubmed/26910909 http://dx.doi.org/10.18632/oncotarget.7469 |
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