MicroRNA-323-3p inhibits cell invasion and metastasis in pancreatic ductal adenocarcinoma via direct suppression of SMAD2 and SMAD3

Pancreatic ductal adenocarcinoma (PDAC), which accounts for 96% of all pancreatic cancer cases, is characterized by rapid progression, invasion and metastasis. Transforming growth factor-beta (TGF-β) signaling is an essential pathway in metastatic progression and microRNAs (miRNA) play central roles...

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Detalles Bibliográficos
Autores principales: Wang, Chunyou, Liu, Pian, Wu, Heshui, Cui, Pengfei, Li, Yongfeng, Liu, Yao, Liu, Zhiqiang, Gou, Shanmiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924761/
https://www.ncbi.nlm.nih.gov/pubmed/26908446
http://dx.doi.org/10.18632/oncotarget.7482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924761/
https://www.ncbi.nlm.nih.gov/pubmed/26908446
http://dx.doi.org/10.18632/oncotarget.7482

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