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MicroRNA-323-3p inhibits cell invasion and metastasis in pancreatic ductal adenocarcinoma via direct suppression of SMAD2 and SMAD3
Pancreatic ductal adenocarcinoma (PDAC), which accounts for 96% of all pancreatic cancer cases, is characterized by rapid progression, invasion and metastasis. Transforming growth factor-beta (TGF-β) signaling is an essential pathway in metastatic progression and microRNAs (miRNA) play central roles...
Autores principales: | Wang, Chunyou, Liu, Pian, Wu, Heshui, Cui, Pengfei, Li, Yongfeng, Liu, Yao, Liu, Zhiqiang, Gou, Shanmiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924761/ https://www.ncbi.nlm.nih.gov/pubmed/26908446 http://dx.doi.org/10.18632/oncotarget.7482 |
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