Cargando…

Immunogenomics reveal molecular circuits of diclofenac induced liver injury in mice

Diclofenac is a non-steroidal anti-inflammatory drug and its use can be associated with severe adverse reactions, notably myocardial infarction, stroke and drug-induced liver injury (DILI). In pursue of immune-mediated DILI mechanisms an immunogenomic study was carried out. Diclofenac treatment of m...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Eun-Hee, Oh, Jung-Hwa, Selvaraj, Saravanakumar, Park, Se-Myo, Choi, Mi-Sun, Spanel, Reinhard, Yoon, Seokjoo, Borlak, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924767/
https://www.ncbi.nlm.nih.gov/pubmed/26934552
http://dx.doi.org/10.18632/oncotarget.7698