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Immunogenomics reveal molecular circuits of diclofenac induced liver injury in mice
Diclofenac is a non-steroidal anti-inflammatory drug and its use can be associated with severe adverse reactions, notably myocardial infarction, stroke and drug-induced liver injury (DILI). In pursue of immune-mediated DILI mechanisms an immunogenomic study was carried out. Diclofenac treatment of m...
Autores principales: | Lee, Eun-Hee, Oh, Jung-Hwa, Selvaraj, Saravanakumar, Park, Se-Myo, Choi, Mi-Sun, Spanel, Reinhard, Yoon, Seokjoo, Borlak, Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924767/ https://www.ncbi.nlm.nih.gov/pubmed/26934552 http://dx.doi.org/10.18632/oncotarget.7698 |
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