Cilengitide in newly diagnosed glioblastoma: biomarker expression and outcome

Integrins αvβ3 and αvβ5 regulate angiogenesis and invasiveness in cancer, potentially by modulating activation of the transforming growth factor (TGF)-β pathway. The randomized phase III CENTRIC and phase II CORE trials explored the integrin inhibitor cilengitide in patients with newly diagnosed gli...

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Detalles Bibliográficos
Autores principales: Weller, Michael, Nabors, Louis Burt, Gorlia, Thierry, Leske, Henning, Rushing, Elisabeth, Bady, Pierre, Hicking, Christine, Perry, James, Hong, Yong-Kil, Roth, Patrick, Wick, Wolfgang, Goodman, Simon L., Hegi, Monika E., Picard, Martin, Moch, Holger, Straub, Josef, Stupp, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924768/
https://www.ncbi.nlm.nih.gov/pubmed/26918452
http://dx.doi.org/10.18632/oncotarget.7588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924768/
https://www.ncbi.nlm.nih.gov/pubmed/26918452
http://dx.doi.org/10.18632/oncotarget.7588

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