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Fatty acid amide hydrolase inhibitors confer anti-invasive and antimetastatic effects on lung cancer cells

Inhibition of endocannabinoid degradation has been suggested as tool for activation of endogenous tumor defense. One of these strategies lies in blockade of fatty acid amide hydrolase (FAAH) which catalyzes the degradation of endocannabinoids (anandamide [AEA], 2-arachidonoylglycerol [2-AG]) and end...

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Detalles Bibliográficos
Autores principales: Winkler, Katrin, Ramer, Robert, Dithmer, Sophie, Ivanov, Igor, Merkord, Jutta, Hinz, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924770/
https://www.ncbi.nlm.nih.gov/pubmed/26930716
http://dx.doi.org/10.18632/oncotarget.7592