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FGFR1 promotes the stem cell-like phenotype of FGFR1-amplified non-small cell lung cancer cells through the Hedgehog pathway

Cancer stem cell-like phenotype is critical for tumor formation and treatment resistance. FGFR1 is found to be amplified in non-small cell lung cancer, particularly in the lung squamous cell cancer (LSCC). Whether FGFR1 contributes to the maintenance of stem cell-like phenotype of FGFR1-amplified lu...

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Detalles Bibliográficos
Autores principales: Ji, Wenxiang, Yu, Yongfeng, Li, Ziming, Wang, Guan, Li, Fan, Xia, Weiliang, Lu, Shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924774/
https://www.ncbi.nlm.nih.gov/pubmed/26936993
http://dx.doi.org/10.18632/oncotarget.7701