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Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome

Mutations in the human MECP2 gene cause Rett syndrome (RTT), a severe neurodevelopmental disorder that predominantly affects girls. Despite decades of work, the molecular function of MeCP2 is not fully understood. Here we report a systematic identification of MeCP2-interacting proteins in the mouse...

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Detalles Bibliográficos
Autores principales: Li, Ronghui, Dong, Qiping, Yuan, Xinni, Zeng, Xin, Gao, Yu, Chiao, Cassandra, Li, Hongda, Zhao, Xinyu, Keles, Sunduz, Wang, Zefeng, Chang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924826/
https://www.ncbi.nlm.nih.gov/pubmed/27352031
http://dx.doi.org/10.1371/journal.pgen.1006129