Cargando…

Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome

Mutations in the human MECP2 gene cause Rett syndrome (RTT), a severe neurodevelopmental disorder that predominantly affects girls. Despite decades of work, the molecular function of MeCP2 is not fully understood. Here we report a systematic identification of MeCP2-interacting proteins in the mouse...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Ronghui, Dong, Qiping, Yuan, Xinni, Zeng, Xin, Gao, Yu, Chiao, Cassandra, Li, Hongda, Zhao, Xinyu, Keles, Sunduz, Wang, Zefeng, Chang, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924826/ https://www.ncbi.nlm.nih.gov/pubmed/27352031 http://dx.doi.org/10.1371/journal.pgen.1006129

Ejemplares similares

CAG repeats mimic CUG repeats in the misregulation of alternative splicing
por: Mykowska, Agnieszka, et al.
Publicado: (2011)

Mechanism and consequence of abnormal calcium homeostasis in Rett syndrome astrocytes
por: Dong, Qiping, et al.
Publicado: (2018)

jMOSAiCS: joint analysis of multiple ChIP-seq datasets
por: Zeng, Xin, et al.
Publicado: (2013)

Unusual misregulation of RNA splicing caused by insertion of a transposable element into the T (Brachyury) locus
por: Goldin, Sarah N, et al.
Publicado: (2003)

Prion-like domain disease-causing mutations and misregulation of alternative splicing relevance in limb-girdle muscular dystrophy (LGMD) 1G
por: Batlle, Cristina, et al.
Publicado: (2020)

The Dct(−/−) Mouse Model to Unravel Retinogenesis Misregulation in Patients with Albinism
por: Tingaud-Sequeira, Angèle, et al.
Publicado: (2022)

SURF: integrative analysis of a compendium of RNA-seq and CLIP-seq datasets highlights complex governing of alternative transcriptional regulation by RNA-binding proteins
por: Chen, Fan, et al.
Publicado: (2020)

Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy
por: Freyermuth, Fernande, et al.
Publicado: (2016)

Misregulated Posttranscriptional Checkpoints: Inflammation and Tumorigenesis
por: Brewer, Gary
Publicado: (2001)

Misregulation of the IgH Locus in Thymocytes
por: Kumari, Gita, et al.
Publicado: (2018)

Cause or Effect: Misregulation of microRNA Pathways in Neurodegeneration
por: Gascon, Eduardo, et al.
Publicado: (2012)

Alternative Therapeutic Intervention for Individuals with Rett Syndrome
por: Lotan, Meir
Publicado: (2007)

Small genomic insertions form enhancers that misregulate oncogenes
por: Abraham, Brian J., et al.
Publicado: (2017)

Transcriptional regulation and its misregulation in Alzheimer’s disease
por: Chen, Xiao-Fen, et al.
Publicado: (2013)

Transcriptional Regulation: Molecules, Involved Mechanisms, and Misregulation
por: Casamassimi, Amelia, et al.
Publicado: (2019)

Misregulation of the expression and activity of DNA methyltransferases in cancer
por: Mensah, Isaiah K, et al.
Publicado: (2021)

Transcriptional Regulation and Its Misregulation in Human Diseases
por: Casamassimi, Amelia, et al.
Publicado: (2023)

Alternative promoters in CpG depleted regions are prevalently associated with epigenetic misregulation of liver cancer transcriptomes
por: Nepal, Chirag, et al.
Publicado: (2023)

Corrigendum: Small genomic insertions form enhancers that misregulate oncogenes
por: Abraham, Brian J., et al.
Publicado: (2017)

An Alternative Splicing Program for Mouse Craniofacial Development
por: Hooper, Joan E., et al.
Publicado: (2020)

Establishment of a Mouse Model with Misregulated Chromosome Condensation due to Defective Mcph1 Function
por: Trimborn, Marc, et al.
Publicado: (2010)

Synaptic FUS accumulation triggers early misregulation of synaptic RNAs in a mouse model of ALS
por: Sahadevan, Sonu, et al.
Publicado: (2021)

Misregulation of Drosophila Myc Disrupts Circadian Behavior and Metabolism
por: Hsieh, Annie L., et al.
Publicado: (2019)

Transcriptional Regulation of Endogenous Retroviruses and Their Misregulation in Human Diseases
por: Zhang, Qian, et al.
Publicado: (2022)

Isogenic Pairs of Wild Type and Mutant Induced Pluripotent Stem Cell (iPSC) Lines from Rett Syndrome Patients as In Vitro Disease Model
por: Ananiev, Gene, et al.
Publicado: (2011)

Survival-Associated Alternative Splicing Events and Prognostic Signatures in Pancreatic Cancer
por: Xu, Lichao, et al.
Publicado: (2020)

Sparse partial least squares regression for simultaneous dimension reduction and variable selection
por: Chun, Hyonho, et al.
Publicado: (2010)

Normalization of ChIP-seq data with control
por: Liang, Kun, et al.
Publicado: (2012)

FreeHi-C simulates high fidelity Hi-C data for benchmarking and data augmentation
por: Zheng, Ye, et al.
Publicado: (2019)

Joint tensor modeling of single cell 3D genome and epigenetic data with Muscle
por: Park, Kwangmoon, et al.
Publicado: (2023)

Dozer: Debiased personalized gene co-expression networks for population-scale scRNA-seq data
por: Lu, Shan, et al.
Publicado: (2023)

Debiased personalized gene coexpression networks for population-scale scRNA-seq data
por: Lu, Shan, et al.
Publicado: (2023)

The Misregulation of Cell Adhesion Components during Tumorigenesis: Overview and Commentary
por: Andl, Claudia D.
Publicado: (2010)

Histone glycation: Linking metabolic perturbation with epigenetic misregulation in cancer
por: Diao, Xiayao
Publicado: (2019)

Regulation of Wnt Signaling Pathways at the Plasma Membrane and Their Misregulation in Cancer
por: Azbazdar, Yagmur, et al.
Publicado: (2021)

VPA Alleviates Neurological Deficits and Restores Gene Expression in a Mouse Model of Rett Syndrome
por: Guo, Weixiang, et al.
Publicado: (2014)

Cell-type-resolved alternative splicing patterns in mouse liver
por: Wu, Peng, et al.
Publicado: (2018)

Rett syndrome
por: Sitholey, Prabhat, et al.
Publicado: (2005)

Dynamic Alternative Splicing During Mouse Preimplantation Embryo Development
por: Xing, Yongqiang, et al.
Publicado: (2020)

Predominant contribution of cis-regulatory divergence in the evolution of mouse alternative splicing
por: Gao, Qingsong, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_1e571cv3bodiv313v5bt9uu8e0