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Pentoxifylline Inhibits WNT Signalling in β-Catenin(high) Patient-Derived Melanoma Cell Populations

BACKGROUND: The heterogeneity of melanoma needs to be addressed and combination therapies seem to be necessary to overcome intrinsic and acquired resistance to newly developed immunotherapies and targeted therapies. Although the role of WNT/β-catenin pathway in melanoma was early demonstrated, its c...

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Detalles Bibliográficos
Autores principales: Talar, Beata, Gajos-Michniewicz, Anna, Talar, Marcin, Chouaib, Salem, Czyz, Malgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924839/
https://www.ncbi.nlm.nih.gov/pubmed/27351373
http://dx.doi.org/10.1371/journal.pone.0158275