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Myeloid Cell Prostaglandin E(2) Receptor EP4 Modulates Cytokine Production but Not Atherogenesis in a Mouse Model of Type 1 Diabetes

Type 1 diabetes mellitus (T1DM) is associated with cardiovascular complications induced by atherosclerosis. Prostaglandin E(2) (PGE(2)) is often raised in states of inflammation, including diabetes, and regulates inflammatory processes. In myeloid cells, a key cell type in atherosclerosis, PGE(2) ac...

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Detalles Bibliográficos
Autores principales: Vallerie, Sara N., Kramer, Farah, Barnhart, Shelley, Kanter, Jenny E., Breyer, Richard M., Andreasson, Katrin I., Bornfeldt, Karin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924840/
https://www.ncbi.nlm.nih.gov/pubmed/27351842
http://dx.doi.org/10.1371/journal.pone.0158316