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Myeloid Cell Prostaglandin E(2) Receptor EP4 Modulates Cytokine Production but Not Atherogenesis in a Mouse Model of Type 1 Diabetes
Type 1 diabetes mellitus (T1DM) is associated with cardiovascular complications induced by atherosclerosis. Prostaglandin E(2) (PGE(2)) is often raised in states of inflammation, including diabetes, and regulates inflammatory processes. In myeloid cells, a key cell type in atherosclerosis, PGE(2) ac...
Autores principales: | Vallerie, Sara N., Kramer, Farah, Barnhart, Shelley, Kanter, Jenny E., Breyer, Richard M., Andreasson, Katrin I., Bornfeldt, Karin E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924840/ https://www.ncbi.nlm.nih.gov/pubmed/27351842 http://dx.doi.org/10.1371/journal.pone.0158316 |
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