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A Novel Di-Leucine Motif at the N-Terminus of Human Organic Solute Transporter Beta Is Essential for Protein Association and Membrane Localization
The heteromeric membrane protein Organic Solute Transporter alpha/beta is the major bile acid efflux transporter in the intestine. Physical association of its alpha and beta subunits is essential for their polarized basolateral membrane localization and function in the transport of bile acids and ot...
Autores principales: | Xu, Shuhua, Soroka, Carol J., Sun, An-Qiang, Backos, Donald S., Mennone, Albert, Suchy, Frederick J., Boyer, James L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924846/ https://www.ncbi.nlm.nih.gov/pubmed/27351185 http://dx.doi.org/10.1371/journal.pone.0158269 |
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