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An Integrated Approach for RNA-seq Data Normalization

BACKGROUND: DNA copy number alteration is common in many cancers. Studies have shown that insertion or deletion of DNA sequences can directly alter gene expression, and significant correlation exists between DNA copy number and gene expression. Data normalization is a critical step in the analysis o...

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Detalles Bibliográficos
Autores principales: Yang, Shengping, Mercante, Donald E., Zhang, Kun, Fang, Zhide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924883/
https://www.ncbi.nlm.nih.gov/pubmed/27385909
http://dx.doi.org/10.4137/CIN.S39781