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An Integrated Approach for RNA-seq Data Normalization
BACKGROUND: DNA copy number alteration is common in many cancers. Studies have shown that insertion or deletion of DNA sequences can directly alter gene expression, and significant correlation exists between DNA copy number and gene expression. Data normalization is a critical step in the analysis o...
Autores principales: | Yang, Shengping, Mercante, Donald E., Zhang, Kun, Fang, Zhide |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924883/ https://www.ncbi.nlm.nih.gov/pubmed/27385909 http://dx.doi.org/10.4137/CIN.S39781 |
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