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Increasing Tumor Accessibility with Conjugatable Disulfide-Bridged Tumor-Penetrating Peptides for Cancer Diagnosis and Treatment

Tumor-homing peptides with tissue-penetrating properties increase the efficacy of targeted cancer therapy by delivering an anticancer agent to the tumor interior. LyP-1 (CGNKRTRGC) and iRGD (CRGDKGPDC) are founding members of this class of peptides. The presence of the cysteines forming the cyclizin...

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Detalles Bibliográficos
Autores principales: Kotamraju, Venkata Ramana, Sharma, Shweta, Kolhar, Poornima, Agemy, Lilach, Pavlovich, James, Ruoslahti, Erkki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924884/
https://www.ncbi.nlm.nih.gov/pubmed/27385913
http://dx.doi.org/10.4137/BCBCR.S29426