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Increasing Tumor Accessibility with Conjugatable Disulfide-Bridged Tumor-Penetrating Peptides for Cancer Diagnosis and Treatment

Tumor-homing peptides with tissue-penetrating properties increase the efficacy of targeted cancer therapy by delivering an anticancer agent to the tumor interior. LyP-1 (CGNKRTRGC) and iRGD (CRGDKGPDC) are founding members of this class of peptides. The presence of the cysteines forming the cyclizin...

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Detalles Bibliográficos
Autores principales:	Kotamraju, Venkata Ramana, Sharma, Shweta, Kolhar, Poornima, Agemy, Lilach, Pavlovich, James, Ruoslahti, Erkki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Libertas Academica 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924884/ https://www.ncbi.nlm.nih.gov/pubmed/27385913 http://dx.doi.org/10.4137/BCBCR.S29426

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