Improved resolution of single channel dwell times reveals mechanisms of binding, priming, and gating in muscle AChR

The acetylcholine receptor (AChR) from vertebrate skeletal muscle initiates voluntary movement, and its kinetics of activation are crucial for maintaining the safety margin for neuromuscular transmission. Furthermore, the kinetic mechanism of the muscle AChR serves as an archetype for understanding...

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Detalles Bibliográficos
Autores principales: Mukhtasimova, Nuriya, daCosta, Corrie J.B., Sine, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924934/
https://www.ncbi.nlm.nih.gov/pubmed/27353445
http://dx.doi.org/10.1085/jgp.201611584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924934/
https://www.ncbi.nlm.nih.gov/pubmed/27353445
http://dx.doi.org/10.1085/jgp.201611584

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