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Improved resolution of single channel dwell times reveals mechanisms of binding, priming, and gating in muscle AChR
The acetylcholine receptor (AChR) from vertebrate skeletal muscle initiates voluntary movement, and its kinetics of activation are crucial for maintaining the safety margin for neuromuscular transmission. Furthermore, the kinetic mechanism of the muscle AChR serves as an archetype for understanding...
Autores principales: | Mukhtasimova, Nuriya, daCosta, Corrie J.B., Sine, Steven M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924934/ https://www.ncbi.nlm.nih.gov/pubmed/27353445 http://dx.doi.org/10.1085/jgp.201611584 |
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