IL-4 sensitivity shapes the peripheral CD8(+) T cell pool and response to infection

Previous studies have revealed that a population of innate memory CD8(+) T cells is generated in response to IL-4, first appearing in the thymus and bearing high expression levels of Eomesodermin (Eomes) but not T-bet. However, the antigen specificity and functional properties of these cells is poor...

Descripción completa

Detalles Bibliográficos
Autores principales: Renkema, Kristin R., Lee, June-Yong, Lee, You Jeong, Hamilton, Sara E., Hogquist, Kristin A., Jameson, Stephen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925014/
https://www.ncbi.nlm.nih.gov/pubmed/27298446
http://dx.doi.org/10.1084/jem.20151359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925014/
https://www.ncbi.nlm.nih.gov/pubmed/27298446
http://dx.doi.org/10.1084/jem.20151359

Ejemplares similares