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IL-4 sensitivity shapes the peripheral CD8(+) T cell pool and response to infection

Previous studies have revealed that a population of innate memory CD8(+) T cells is generated in response to IL-4, first appearing in the thymus and bearing high expression levels of Eomesodermin (Eomes) but not T-bet. However, the antigen specificity and functional properties of these cells is poor...

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Detalles Bibliográficos
Autores principales:	Renkema, Kristin R., Lee, June-Yong, Lee, You Jeong, Hamilton, Sara E., Hogquist, Kristin A., Jameson, Stephen C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2016
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925014/ https://www.ncbi.nlm.nih.gov/pubmed/27298446 http://dx.doi.org/10.1084/jem.20151359

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