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Comprehensive Genomic Profiling of Orbital and Ocular Adnexal Lymphomas Identifies Frequent Alterations in MYD88 and Chromatin Modifiers: New Routes to Targeted Therapies

Non-Hodgkin lymphoma of the orbit and ocular adnexa is the most common primary orbital malignancy. Treatments for low- (extra-nodal marginal zone and follicular lymphomas) and high-grade (diffuse large B-cell lymphoma) are associated with local and vision-threatening toxicities. High-grade lymphomas...

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Detalles Bibliográficos
Autores principales: Cani, Andi K., Soliman, Moaaz, Hovelson, Daniel H., Liu, Chia-Jen, McDaniel, Andrew S., Haller, Michaela J., Bratley, Jarred, Rahrig, Samantha, Li, Qiang, Briceño, César A., Tomlins, Scott A., Rao, Rajesh C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925176/
https://www.ncbi.nlm.nih.gov/pubmed/27102345
http://dx.doi.org/10.1038/modpathol.2016.79