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An epigenetic mechanism mediates developmental nicotine effects on neuronal structure and behavior

Developmental nicotine exposure causes persistent changes in cortical neuron morphology and in behavior. We used microarray screening to identify master transcriptional or epigenetic regulators mediating these effects of nicotine and discovered increases in Ash2l, a component of a histone methyltran...

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Detalles Bibliográficos
Autores principales: Jung, Yonwoo, Hsieh, Lawrence S., Lee, Angela M., Zhou, Zhifeng, Coman, Daniel, Heath, Christopher J., Hyder, Fahmeed, Mineur, Yann S., Yuan, Qiaoping, Goldman, David, Bordey, Angelique, Picciotto, Marina R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925298/
https://www.ncbi.nlm.nih.gov/pubmed/27239938
http://dx.doi.org/10.1038/nn.4315