Polysialic Acid Acute Depletion Induces Structural Plasticity in Interneurons and Impairs the Excitation/Inhibition Balance in Medial Prefrontal Cortex Organotypic Cultures

The structure and function of the medial prefrontal cortex (mPFC) is affected in several neuropsychiatric disorders, including schizophrenia and major depression. Recent studies suggest that imbalances between excitatory and inhibitory activity (E/I) may be responsible for this cortical dysfunction...

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Detalles Bibliográficos
Autores principales: Castillo-Gómez, Esther, Pérez-Rando, Marta, Vidueira, Sandra, Nacher, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925659/
https://www.ncbi.nlm.nih.gov/pubmed/27445697
http://dx.doi.org/10.3389/fncel.2016.00170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925659/
https://www.ncbi.nlm.nih.gov/pubmed/27445697
http://dx.doi.org/10.3389/fncel.2016.00170

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