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Quantification of global mitochondrial DNA methylation levels and inverse correlation with age at two CpG sites

Mammalian ageing features biological attrition evident at cellular, genetic and epigenetic levels. Mutation of mitochondrial DNA, and nuclear DNA methylation changes are well established correlates of ageing. The methylation of mitochondrial DNA (mtDNA) is a new and incompletely described phenomenon...

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Detalles Bibliográficos
Autores principales: Mawlood, Shakhawan K., Dennany, Lynn, Watson, Nigel, Dempster, John, Pickard, Benjamin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925819/
https://www.ncbi.nlm.nih.gov/pubmed/26887692
http://dx.doi.org/10.18632/aging.100892