Aging causes decreased resistance to multiple stresses and a failure to activate specific stress response pathways

In this work, we examine the relationship between stress resistance and aging. We find that resistance to multiple types of stress peaks during early adulthood and then declines with age. To dissect the underlying mechanisms, we use C. elegans transcriptional reporter strains that measure the activa...

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Detalles Bibliográficos
Autores principales: Dues, Dylan J., Andrews, Emily K., Schaar, Claire E., Bergsma, Alexis L., Senchuk, Megan M., Van Raamsdonk, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925828/
https://www.ncbi.nlm.nih.gov/pubmed/27053445
http://dx.doi.org/10.18632/aging.100939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925828/
https://www.ncbi.nlm.nih.gov/pubmed/27053445
http://dx.doi.org/10.18632/aging.100939

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