Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers

Mitochondria are key players in aging and in the pathogenesis of age-related diseases. Recent mitochondrial transcriptome analyses revealed the existence of multiple small mRNAs transcribed from mitochondrial DNA (mtDNA). Humanin (HN), a peptide encoded in the mtDNA 16S ribosomal RNA region, is a ne...

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Detalles Bibliográficos
Autores principales: Cobb, Laura J., Lee, Changhan, Xiao, Jialin, Yen, Kelvin, Wong, Richard G., Nakamura, Hiromi K., Mehta, Hemal H., Gao, Qinglei, Ashur, Carmel, Huffman, Derek M., Wan, Junxiang, Muzumdar, Radhika, Barzilai, Nir, Cohen, Pinchas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925829/
https://www.ncbi.nlm.nih.gov/pubmed/27070352
http://dx.doi.org/10.18632/aging.100943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925829/
https://www.ncbi.nlm.nih.gov/pubmed/27070352
http://dx.doi.org/10.18632/aging.100943

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