Mitotic degradation of yeast Fkh1 by the Anaphase Promoting Complex is required for normal longevity, genomic stability and stress resistance

The Saccharomyces cerevisiae Forkhead Box (Fox) orthologs, Forkheads (Fkh) 1 and 2, are conserved transcription factors required for stress response, cell cycle progression and longevity. These yeast proteins play a key role in mitotic progression through activation of the ubiquitin E3 ligase Anapha...

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Detalles Bibliográficos
Autores principales: Malo, Mackenzie E., Postnikoff, Spike D.L., Arnason, Terra G., Harkness, Troy A.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925830/
https://www.ncbi.nlm.nih.gov/pubmed/27099939
http://dx.doi.org/10.18632/aging.100949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925830/
https://www.ncbi.nlm.nih.gov/pubmed/27099939
http://dx.doi.org/10.18632/aging.100949

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