Cortical amyloid burden and age moderate hippocampal activity in cognitively-normal adults

Neurodegeneration in the medial temporal lobe, particularly in the hippocampus, is viewed as the primary source of AD-related memory deficits. Yet, in the earliest preclinical phase of Alzheimer's disease (AD), amyloid-beta (Aβ) plaques deposit primarily in the neocortex, not in the medial temp...

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Detalles Bibliográficos
Autores principales: Song, Zhuang, McDonough, Ian M., Liu, Peiying, Lu, Hanzhang, Park, Denise C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925884/
https://www.ncbi.nlm.nih.gov/pubmed/27408792
http://dx.doi.org/10.1016/j.nicl.2016.05.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925884/
https://www.ncbi.nlm.nih.gov/pubmed/27408792
http://dx.doi.org/10.1016/j.nicl.2016.05.013

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