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Metformin Alleviated Aβ-Induced Apoptosis via the Suppression of JNK MAPK Signaling Pathway in Cultured Hippocampal Neurons

Both diabetes and hyperinsulinemia are confirmed risk factors for Alzheimer's disease. Some researchers proposed that antidiabetic drugs may be used as disease-modifying therapies, such as metformin and thiazolidinediones, although more evidence was poorly supported. The aim of the current stud...

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Detalles Bibliográficos
Autores principales: Chen, Bin, Teng, Ying, Zhang, Xingguang, Lv, Xiaofeng, Yin, Yanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925968/
https://www.ncbi.nlm.nih.gov/pubmed/27403417
http://dx.doi.org/10.1155/2016/1421430