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Osteopontin deficiency reduces kidney damage from hypercholesterolemia in Apolipoprotein E-deficient mice

Hypercholesterolemia is a well-established risk factor for kidney injury, which can lead to chronic kidney disease (CKD). Osteopontin (OPN) has been implicated in the pathology of several renal conditions. This study was to evaluate the effects of OPN on hypercholesterolemia induced renal dysfunctio...

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Detalles Bibliográficos
Autores principales: Pei, Zouwei, Okura, Takafumi, Nagao, Tomoaki, Enomoto, Daijiro, Kukida, Masayoshi, Tanino, Akiko, Miyoshi, Ken-ichi, Kurata, Mie, Higaki, Jitsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926090/
https://www.ncbi.nlm.nih.gov/pubmed/27353458
http://dx.doi.org/10.1038/srep28882