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Osteopontin deficiency reduces kidney damage from hypercholesterolemia in Apolipoprotein E-deficient mice
Hypercholesterolemia is a well-established risk factor for kidney injury, which can lead to chronic kidney disease (CKD). Osteopontin (OPN) has been implicated in the pathology of several renal conditions. This study was to evaluate the effects of OPN on hypercholesterolemia induced renal dysfunctio...
Autores principales: | Pei, Zouwei, Okura, Takafumi, Nagao, Tomoaki, Enomoto, Daijiro, Kukida, Masayoshi, Tanino, Akiko, Miyoshi, Ken-ichi, Kurata, Mie, Higaki, Jitsuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926090/ https://www.ncbi.nlm.nih.gov/pubmed/27353458 http://dx.doi.org/10.1038/srep28882 |
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