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Use of VacA as a Vaccine Antigen

One of the major toxins secreted by H. pylori is the Vacuolating cytotoxin A (VacA) named after its ability to induce the formation of “vacuole”-like membrane vesicles in the cytoplasm of gastric cells. VacA has been associated with the disruption of mitochondrial functions, stimulation of apoptosis...

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Detalles Bibliográficos
Autores principales: Moyat, Mati, Velin, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926147/
https://www.ncbi.nlm.nih.gov/pubmed/27338474
http://dx.doi.org/10.3390/toxins8060181