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Lambda gpP-DnaB Helicase Sequestration and gpP-RpoB Associated Effects: On Screens for Auxotrophs, Selection for Rif(R), Toxicity, Mutagenicity, Plasmid Curing

The bacteriophage lambda replication initiation protein P exhibits a toxic effect on its Escherichia coli (E. coli) host, likely due to the formation of a dead-end P-DnaB complex, sequestering the replicative DnaB helicase from further activity. Intracellular expression of P triggers SOS-independent...

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Detalles Bibliográficos
Autores principales: Hayes, Sidney, Wang, Wen, Rajamanickam, Karthic, Chu, Audrey, Banerjee, Anirban, Hayes, Connie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926192/
https://www.ncbi.nlm.nih.gov/pubmed/27338450
http://dx.doi.org/10.3390/v8060172