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Lambda gpP-DnaB Helicase Sequestration and gpP-RpoB Associated Effects: On Screens for Auxotrophs, Selection for Rif(R), Toxicity, Mutagenicity, Plasmid Curing
The bacteriophage lambda replication initiation protein P exhibits a toxic effect on its Escherichia coli (E. coli) host, likely due to the formation of a dead-end P-DnaB complex, sequestering the replicative DnaB helicase from further activity. Intracellular expression of P triggers SOS-independent...
Autores principales: | Hayes, Sidney, Wang, Wen, Rajamanickam, Karthic, Chu, Audrey, Banerjee, Anirban, Hayes, Connie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926192/ https://www.ncbi.nlm.nih.gov/pubmed/27338450 http://dx.doi.org/10.3390/v8060172 |
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