Common molecular mechanism of amyloid pore formation by Alzheimer’s β-amyloid peptide and α-synuclein

Calcium-permeable pores formed by small oligomers of amyloid proteins are the primary pathologic species in Alzheimer’s and Parkinson’s diseases. However, the molecular mechanisms underlying the assembly of these toxic oligomers in the plasma membrane of brain cells remain unclear. Here we have anal...

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Detalles Bibliográficos
Autores principales: Di Scala, Coralie, Yahi, Nouara, Boutemeur, Sonia, Flores, Alessandra, Rodriguez, Léa, Chahinian, Henri, Fantini, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926208/
https://www.ncbi.nlm.nih.gov/pubmed/27352802
http://dx.doi.org/10.1038/srep28781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926208/
https://www.ncbi.nlm.nih.gov/pubmed/27352802
http://dx.doi.org/10.1038/srep28781

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