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Common molecular mechanism of amyloid pore formation by Alzheimer’s β-amyloid peptide and α-synuclein
Calcium-permeable pores formed by small oligomers of amyloid proteins are the primary pathologic species in Alzheimer’s and Parkinson’s diseases. However, the molecular mechanisms underlying the assembly of these toxic oligomers in the plasma membrane of brain cells remain unclear. Here we have anal...
Autores principales: | Di Scala, Coralie, Yahi, Nouara, Boutemeur, Sonia, Flores, Alessandra, Rodriguez, Léa, Chahinian, Henri, Fantini, Jacques |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926208/ https://www.ncbi.nlm.nih.gov/pubmed/27352802 http://dx.doi.org/10.1038/srep28781 |
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