Synthetic small molecule GLP-1 secretagogues prepared by means of a three-component indole annulation strategy

Rational assembly of small molecule libraries for purposes of drug discovery requires an efficient approach in which the synthesis of bioactive compounds is enabled so that numerous structurally related compounds of a similar basic formulation can be derived. Here, we describe (4 + 3) and (3 + 2) in...

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Detalles Bibliográficos
Autores principales: Chepurny, Oleg G., Leech, Colin A., Tomanik, Martin, DiPoto, Maria C., Li, Hui, Han, Xinping, Meng, Qinghe, Cooney, Robert N., Wu, Jimmy, Holz, George G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926213/
https://www.ncbi.nlm.nih.gov/pubmed/27352904
http://dx.doi.org/10.1038/srep28934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926213/
https://www.ncbi.nlm.nih.gov/pubmed/27352904
http://dx.doi.org/10.1038/srep28934

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