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Synthetic small molecule GLP-1 secretagogues prepared by means of a three-component indole annulation strategy
Rational assembly of small molecule libraries for purposes of drug discovery requires an efficient approach in which the synthesis of bioactive compounds is enabled so that numerous structurally related compounds of a similar basic formulation can be derived. Here, we describe (4 + 3) and (3 + 2) in...
Autores principales: | Chepurny, Oleg G., Leech, Colin A., Tomanik, Martin, DiPoto, Maria C., Li, Hui, Han, Xinping, Meng, Qinghe, Cooney, Robert N., Wu, Jimmy, Holz, George G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926213/ https://www.ncbi.nlm.nih.gov/pubmed/27352904 http://dx.doi.org/10.1038/srep28934 |
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