Cargando…

Site-specific covalent modifications of human insulin by catechol estrogens: Reactivity and induced structural and functional changes

Proteins, covalently modified by catechol estrogens (CEs), were identified recently from the blood serum of diabetic patients and referred to as estrogenized proteins. Estrogenization of circulating insulin may occur and affect its molecular functioning. Here, the chemical reactivity of CEs towards...

Descripción completa

Detalles Bibliográficos
Autores principales: Ku, Ming-Chun, Fang, Chieh-Ming, Cheng, Juei-Tang, Liang, Huei-Chen, Wang, Tzu-Fan, Wu, Chih-Hsing, Chen, Chiao-Chen, Tai, Jung-Hsiang, Chen, Shu-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926285/
https://www.ncbi.nlm.nih.gov/pubmed/27353345
http://dx.doi.org/10.1038/srep28804