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Site-specific covalent modifications of human insulin by catechol estrogens: Reactivity and induced structural and functional changes
Proteins, covalently modified by catechol estrogens (CEs), were identified recently from the blood serum of diabetic patients and referred to as estrogenized proteins. Estrogenization of circulating insulin may occur and affect its molecular functioning. Here, the chemical reactivity of CEs towards...
Autores principales: | Ku, Ming-Chun, Fang, Chieh-Ming, Cheng, Juei-Tang, Liang, Huei-Chen, Wang, Tzu-Fan, Wu, Chih-Hsing, Chen, Chiao-Chen, Tai, Jung-Hsiang, Chen, Shu-Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926285/ https://www.ncbi.nlm.nih.gov/pubmed/27353345 http://dx.doi.org/10.1038/srep28804 |
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