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Kidney Injury Molecule-1 Is Specifically Expressed in Cystically-Transformed Proximal Tubules of the PKD/Mhm (cy/+) Rat Model of Polycystic Kidney Disease

Expression of kidney injury molecule-1 (Kim-1) is rapidly upregulated following tubular injury, constituting a biomarker for acute kidney damage. We examined the renal localization of Kim-1 expression in PKD/Mhm (polycystic kidney disease, Mannheim) (cy/+) rats (cy: mutated allel, +: wild type allel...

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Detalles Bibliográficos
Autores principales: Gauer, Stefan, Urbschat, Anja, Gretz, Norbert, Hoffmann, Sigrid C., Kränzlin, Bettina, Geiger, Helmut, Obermüller, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926336/
https://www.ncbi.nlm.nih.gov/pubmed/27231899
http://dx.doi.org/10.3390/ijms17060802