Identification of Protein–Excipient Interaction Hotspots Using Computational Approaches

Protein formulation development relies on the selection of excipients that inhibit protein–protein interactions preventing aggregation. Empirical strategies involve screening many excipient and buffer combinations using force degradation studies. Such methods do not readily provide information on in...

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Detalles Bibliográficos
Autores principales: Barata, Teresa S., Zhang, Cheng, Dalby, Paul A., Brocchini, Steve, Zloh, Mire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926387/
https://www.ncbi.nlm.nih.gov/pubmed/27258262
http://dx.doi.org/10.3390/ijms17060853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926387/
https://www.ncbi.nlm.nih.gov/pubmed/27258262
http://dx.doi.org/10.3390/ijms17060853

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