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v-Src Causes Chromosome Bridges in a Caffeine-Sensitive Manner by Generating DNA Damage

An increase in Src activity is commonly observed in epithelial cancers. Aberrant activation of the kinase activity is associated with malignant progression. However, the mechanisms that underlie the Src-induced malignant progression of cancer are not completely understood. We show here that v-Src, a...

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Detalles Bibliográficos
Autores principales: Ikeuchi, Masayoshi, Fukumoto, Yasunori, Honda, Takuya, Kuga, Takahisa, Saito, Youhei, Yamaguchi, Naoto, Nakayama, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926405/
https://www.ncbi.nlm.nih.gov/pubmed/27271602
http://dx.doi.org/10.3390/ijms17060871