Intravenous Administration Is an Effective and Safe Route for Cancer Gene Therapy Using the Bifidobacterium-Mediated Recombinant HSV-1 Thymidine Kinase and Ganciclovir

The herpes simplex virus thymidine kinase/ganciclovir (HSV TK/GCV) system is one of the best studied cancer suicide gene therapy systems. Our previous study showed that caspase 3 expression was upregulated and bladder tumor growth was significantly reduced in rats treated with a combination of Bifid...

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Detalles Bibliográficos
Autores principales: Zhou, Huicong, He, Zhiliang, Wang, Changdong, Xie, Tingting, Liu, Lin, Liu, Chuanyang, Song, Fangzhou, Ma, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926425/
https://www.ncbi.nlm.nih.gov/pubmed/27275821
http://dx.doi.org/10.3390/ijms17060891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926425/
https://www.ncbi.nlm.nih.gov/pubmed/27275821
http://dx.doi.org/10.3390/ijms17060891

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