p38 MAPK Inhibitor Insufficiently Attenuates HSC Senescence Administered Long-Term after 6 Gy Total Body Irradiation in Mice

Senescent hematopoietic stem cells (HSCs) accumulate with age and exposure to stress, such as total-body irradiation (TBI), which may cause long-term myelosuppression in the clinic. However, the methods available for long-term myelosuppression remain limited. Previous studies have demonstrated that...

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Detalles Bibliográficos
Autores principales: Lu, Lu, Wang, Yue-Ying, Zhang, Jun-Ling, Li, De-Guan, Meng, Ai-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926439/
https://www.ncbi.nlm.nih.gov/pubmed/27338355
http://dx.doi.org/10.3390/ijms17060905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926439/
https://www.ncbi.nlm.nih.gov/pubmed/27338355
http://dx.doi.org/10.3390/ijms17060905

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