Persistence of HCV in Acutely-Infected Patients Depletes C24-Ceramide and Upregulates Sphingosine and Sphinganine Serum Levels

Hepatitis C virus (HCV) substantially affects lipid metabolism, and remodeling of sphingolipids appears to be essential for HCV persistence in vitro. The aim of the current study is the evaluation of serum sphingolipid variations during acute HCV infection. We enrolled prospectively 60 consecutive p...

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Detalles Bibliográficos
Autores principales: Grammatikos, Georgios, Dietz, Julia, Ferreiros, Nerea, Koch, Alexander, Dultz, Georg, Bon, Dimitra, Karakasiliotis, Ioannis, Lutz, Thomas, Knecht, Gaby, Gute, Peter, Herrmann, Eva, Zeuzem, Stefan, Mavromara, Penelope, Sarrazin, Christoph, Pfeilschifter, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926455/
https://www.ncbi.nlm.nih.gov/pubmed/27304952
http://dx.doi.org/10.3390/ijms17060922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926455/
https://www.ncbi.nlm.nih.gov/pubmed/27304952
http://dx.doi.org/10.3390/ijms17060922

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