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Persistence of HCV in Acutely-Infected Patients Depletes C24-Ceramide and Upregulates Sphingosine and Sphinganine Serum Levels
Hepatitis C virus (HCV) substantially affects lipid metabolism, and remodeling of sphingolipids appears to be essential for HCV persistence in vitro. The aim of the current study is the evaluation of serum sphingolipid variations during acute HCV infection. We enrolled prospectively 60 consecutive p...
Autores principales: | Grammatikos, Georgios, Dietz, Julia, Ferreiros, Nerea, Koch, Alexander, Dultz, Georg, Bon, Dimitra, Karakasiliotis, Ioannis, Lutz, Thomas, Knecht, Gaby, Gute, Peter, Herrmann, Eva, Zeuzem, Stefan, Mavromara, Penelope, Sarrazin, Christoph, Pfeilschifter, Josef |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926455/ https://www.ncbi.nlm.nih.gov/pubmed/27304952 http://dx.doi.org/10.3390/ijms17060922 |
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