Kynurenine Aminotransferase Isozyme Inhibitors: A Review

Kynurenine aminotransferase isozymes (KATs 1–4) are members of the pyridoxal-5’-phosphate (PLP)-dependent enzyme family, which catalyse the permanent conversion of l-kynurenine (l-KYN) to kynurenic acid (KYNA), a known neuroactive agent. As KATs are found in the mammalian brain and have key roles in...

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Detalles Bibliográficos
Autores principales: Nematollahi, Alireza, Sun, Guanchen, Jayawickrama, Gayan S., Church, W. Bret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926479/
https://www.ncbi.nlm.nih.gov/pubmed/27314340
http://dx.doi.org/10.3390/ijms17060946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926479/
https://www.ncbi.nlm.nih.gov/pubmed/27314340
http://dx.doi.org/10.3390/ijms17060946

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